Fourteen years ago, Dr. Karl Matthews, head of Government Biolab 83, is savagely murdered by ancient soul-taker, MR. HELL. Today, Dr. Matthews' daughter, Tyler, has returned to the scene of her father's death. Unknown to Tyler, MR. HELL has also returned. To complicate this house of horrors, a group of mercenaries has invaded the lab to steal a deadly vial of bacterium. Many will soon suffer grisly deaths, along with having their eyes(the windows to the soul)harvested by MR. HELL.

The middle-class couple Linda Hanson and Jim Hanson lives a wasted and routine relationship with their two daughters in their comfortable house in the suburbs. On a Thursday morning, the local sheriff visits Linda and tells her that her husband died in a car accident on the previous day. On the next morning, when Linda awakes, she finds Jim safe and sound at home. When she awakes on the next morning, she realizes that her days are out of order, but her family and friends believe she is insane.